Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
An attempt to the study epidemiological, clinical and therapeutic effects is the need since it results in psychological and physical problems. A prospective study was undertaken in the department of Dermatology, Venerology and Leprology attending outpatient department among the patients with acne vulgaris. A total of 160 cases of acne vulgaris constituted the sample size. The incidence of acne in this study was 4.58% for a period of 1 years and 10 months. About 60.6% of the study subjects belonged to 16‐20 years of age group and 62.5% of the males and 59.6% of the females were aged between 16‐20 years. This study had shown that, about 65% of the patients with acne were females. 60.6% of the patients with acne were students. The acne was aggravated by using cosmetics in 66.9% of the cases, stress in 48.1% of the cases and premenstrual flare was present in 47.1% of the females. About 28.1% of the patients complained that the acne aggravates during summer and during winter in 13.8% of the cases. About 91.3% of the acne patients in this study had oily skin. Face was common site of lesion in 71.3% of the cases, 10% had acne on face, back and chest and 9.4% had acne on face and back. 154 out of 160 patients had comedones. Comedones were predominant in 16‐20 of age group. About 60.4% of males and 58.4% of females with Comedones were aged between 16‐20 years. This study had shown that, the papules were found in 154 out of 160 patients of which 101 were males and 53 were females. The papules were predominant in 16‐20 years of age of both the sexes. The ice pick scar was present in 10% of the cases, Boxcar scar was present in 4.4%, Rolling scar was present in 4.4% of the cases. This study had shown that, response topical Clindamycin 1% gel in grade I and Grade II acne was excellent to good in 50% of the cases and fair in 50% of the cases. The response to topical adapalene 0.1% with Benzoyl Peroxide 2.5% (Combination) was excellent to good in 44.4% of the cases in grade I lesions and 55.6% had fair response. Among Arade II lesions 50.0% had excellent to good response and fair response in grade II lesions. About 44.4% of the grade I lesions had excellent to good response and 55.6% had fair response. In grade II lesions, 57.1% had excellent to good response and 50% had fair response. Using Topical Adapalene 0.1% gel, all the patients with grade II lesions had fair response and 53.8% had excellent to fair response and 46.2% had fair response. The use of Topical benzoyl peroxide 5% gel had shown that, 50% had excellent to good response and 50% had fair response with grade I lesions. In Grade II lesions, 75.0% had excellent to good response and 25.0% had fair response. By using Azelaic acid 20% cream, 60% of the grade I lesions had excellent to good response and 40% had fair response. In the grade II lesions, 55.6% had excellent to good response and 44.0% had fair response. This regimen had shown excellent to good response in 50% of the grade I lesions and fair response in 50% of the patients. In grade II lesions, excellent to good response was found in 50% of the cases and fair response in 50.0% of the cases. This regimen had shown that, 50.0% with grade I lesions had excellent to good response and 50% had fair response. In grade II lesions, 55.6% had excellent to good response and 44.4% had fair response. Topical Clindamycin and Topical adapalene and benzoyl peroxide combination had shown mild dryness and burning sensation in small proportion of the patients in this study. Tretinoin gel had shown erythema, scaling, burning and dryness. Adapalene gel was well tolerated than the tretinoin. The benzoyl peroxide and its combinations had shown mild scaling, burning and itching.
How to cite this article:
M. Kowshik Kumar and V. Bhargava Ram. A Study of Clinico‐Epidemiological Study and Topical Therapy of Acne Vulgaris.
DOI: https://doi.org/10.36478/10.36478/makrjms.2021.112.119
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2021.112.119