Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
Vitiligo is a chronic acquired depigmenting disorder characterized by the selective loss of melanocytes, resulting in well-defined depigmented macules and patches. Although the disease is not life- hreatening, it has significant cosmetic, psychological, and social implications. Understanding its clinical and epidemiological profile is essential for early diagnosis and effective management. Aim of the study was to evaluate the clinical and epidemiological profile of patients with vitiligo attending the Dermatology, Venereology and Leprosy (DVL) Outpatient Department of Mamata Medical College and General Hospital, Khammam. A hospital-based descriptive cross-sectional study was conducted among 75 clinically diagnosed vitiligo patients attending the Dermatology OPD. Demographic details, clinical history, family history, disease characteristics, associated comorbidities, and clinical examination findings were recorded using a pre-designed structured proforma. The collected data were analyzed using SPSS software. Descriptive statistics were expressed as frequencies, percentages, mean, and standard deviation, while Chi-square test was applied to determine associations. A p-value of <0.05 was considered statistically significant. The majority of patients belonged to the 11-20-year age group, with a slight female predominance. Vitiligo vulgaris was the most common clinical subtype, and the face was the most frequent initial site of involvement. Progressive disease was observed in most patients. A positive family history was noted in approximately one-fifth of cases. Autoimmune thyroid disease was the commonest associated comorbidity. A significant association was observed between family history and generalized vitiligo, while longer disease duration was significantly associated with leukotrichia (p<0.05). Vitiligo predominantly affected adolescents and young adults, with vitiligo vulgaris being the commonest clinical presentation. Early recognition, comprehensive clinical evaluation, and screening for associated autoimmune disorders may facilitate timely intervention and improve patient outcomes and quality of life.
How to cite this article:
Dr. Bikkasani U.P. Lakshmi Kishan Rao. Clinical and Epidemiological Profile of Patients with Vitiligo Attending aTertiary Care Dermatology Outpatient Department: A Cross-Sectional Study.
DOI: https://doi.org/10.36478/10.36478/makrjms.2014.191.196
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2014.191.196