Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Attempts were made to differentiate between effect of laryngoscopy and those of tracheal intubation and their individual contribution to hemodynamic changes. Prys Roberts et al. (1971) observed that a majority of patients produced reflex tachycardia and hypertension well before the act of intubation. So it is laryngoscopy rather than endotracheal intubation which generates the stimulus. A correlation between pressor response and plasma catecholamine concentration is implicated in causation of this hemodynamic response. All the patients were visited the day before surgery and pre anaesthetic counselling done. All the patients received Tab alprazolam 0.5 mg night before the surgery. On the day of surgery intravenous line was secured. On entering the OT, pulse oximeter, non‐invasive BP, ECG monitors were connected. A baseline heart rate, systolic and diastolic blood pressure, SpO2 were recorded (BL‐baseline). After giving the loading dose of dexmedetomidine there was more fall in SBP, also at the time of laryngoscopy the rise in SBP was lesser in dexmedetomidine group keeping parameters closer to baseline values. It is also observed that the return to baseline values was faster in dexmedetomidine group than in clonidine group.
How to cite this article:
V. Divya, Karthikeya Jampala and K. Radhika. Efficacy of Dexmedetomidine Versus Clonidine in Attenuating Hemodynamic Response to Laryngoscopy and Intubation.
DOI: https://doi.org/10.36478/0.59218/makrjms.2024.5.289.292
URL: https://www.makhillpublications.co/view-article/1815-9346/0.59218/makrjms.2024.5.289.292