files/journal/2022-09-02_12-30-09-000000_653.png

Journal of Animal and Veterinary Advances

ISSN: Online 1993-601X
ISSN: Print 1680-5593
79
Views
0
Downloads

Effect of Chinese Medicine Effective Component Prescription of Chickens Immune Organ CD4+, CD8+ After IBDV Infected

Guisheng Gao, Qiumei Shi, Guangping Gao , Yanying Zhang , Jianzhong Xu and Ping Shen
Page: 660-663 | Received 21 Sep 2022, Published online: 21 Sep 2022

Full Text Reference XML File PDF File

Abstract

To elucidate the pharmaceutical mechanism about the prevention and treatment effects of Zihuangsan, so as to provide theoretical basis on animal production. The 240, 1 day old chickens were acclimatized for 6 days and then randomly divided into groups A, B, C, D, E and F, 40 birds in each group. The birds in group A, B and C were administered with three dose such as high, middle and low of Chinese Medicine Prescription-Zihuangsan. The chickens in groups D, E and F were given with the same volume of Normal Saline (NS). The birds in groups A, B, C, D and E were infected with IBDV by eye drop, group F as normal control by using NS instead of IBDV and Zihuangsan. The 3 days after IBDV infected, 0.5 mL yolk antibody per bird in group D was given intramuscularly. Result show Zihuangsan could significantly reduce the chicken’s mortality and increase the development of positive expression of CD4+, CD8+ T in immune organs such as thymus and intestinal. Zihuangsan could regulate the immune deficiency caused by IBDV. The best dosage of Zihuangsan is middle dose.


How to cite this article:

Guisheng Gao, Qiumei Shi, Guangping Gao , Yanying Zhang , Jianzhong Xu and Ping Shen . Effect of Chinese Medicine Effective Component Prescription of Chickens Immune Organ CD4+, CD8+ After IBDV Infected.
DOI: https://doi.org/10.36478/javaa.2013.660.663
URL: https://www.makhillpublications.co/view-article/1680-5593/javaa.2013.660.663