Journal of Animal and Veterinary Advances
ISSN: Online 1993-601XISSN: Print 1680-5593
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Sedative and Anticonvulsant Properties of the Decoction of Balanites aegyptiaca (Balanitaceae)
Elisabeth Ngo Bum , Neteydji Sidiki , Taiwe , Paul Fasutin Seke Etet , Frededic Maidawa , Silvere Vincent Rakotonirina and Alice Rakotonirina
Page: 34-38 | Received 21 Sep 2022, Published online: 21 Sep 2022
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Abstract
The decoction of Balanites aegyptiaca, a plant used in traditional medicine in Africa for many diseases, possesses anticonvulsant and sedative activity in mice. This decoction protected mice against strychnine- and pentylenetetrazol-induced seizures. But Balanites aegyptiaca decoction had no effect against picrotoxin-induced seizures. In the other side, the decoction of Balanites aegyptiaca potentiated sleep-induced by diazepam. The total sleep time of the control group was multiply by 4 in the presence of the decoction at a dose of 1000 mg /kg (from 12 to 59 min). With these effects, the decoction of Balanites aegyptiaca L. seem to posses sedative and anticonvulsant properties that might explain its use as a traditional medicine for epilepsy in Africa.
How to cite this article:
Elisabeth Ngo Bum , Neteydji Sidiki , Taiwe , Paul Fasutin Seke Etet , Frededic Maidawa , Silvere Vincent Rakotonirina and Alice Rakotonirina . Sedative and Anticonvulsant Properties of the Decoction
of Balanites aegyptiaca (Balanitaceae).
DOI: https://doi.org/10.36478/javaa.2005.34.38
URL: https://www.makhillpublications.co/view-article/1680-5593/javaa.2005.34.38