Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Type 2 diabetes mellitus is commonly associated with lipid abnormalities, which increase the risk of atherosclerosis and cardiovascular disease. Diabetic dyslipidemia is usually characterized by raised triglycerides, raised LDL cholesterol, raised VLDL cholesterol and low HDL cholesterol. Early detection of lipid abnormalities is important for reducing future vascular complications. Aim was to study the lipid profile pattern among patients with type 2 diabetes mellitus. This hospital-based observational study was conducted in the Department of General Medicine, Mamata Medical College and General Hospital, Khammam. A total of 75 patients with type 2 diabetes mellitus were included. Detailed clinical history, examination findings and relevant laboratory parameters were recorded. Fasting blood sugar, postprandial blood sugar, HbA1c and fasting lipid profile were analyzed. Data were expressed as frequency, percentage, mean and standard deviation. Chi-square test was used to assess associations, and p-value <0.05 was considered statistically significant. Dyslipidemia was observed in 57 patients (76%). Raised LDL cholesterol was the most common abnormality, seen in 50 patients (66.7%), followed by raised triglycerides in 48 patients (64%), raised VLDL cholesterol in 46 patients (61.3%), low HDL cholesterol in 43 patients (57.3%) and raised total cholesterol in 41 patients (54.7%). Dyslipidemia was significantly associated with poor glycemic control and increased BMI. Dyslipidemia is highly prevalent among patients with type 2 diabetes mellitus. Routine lipid profile screening should be performed in all diabetic patients to identify cardiovascular risk early.
How to cite this article:
B. Nageswara Rao. A Study of Lipid Profile Abnormalities in Patients with Type 2 Diabetes Mellitus at a Tertiary Care Hospital.
DOI: https://doi.org/10.36478/10.36478/makrjms.2016.778.784
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2016.778.784