Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Thyroid dysfunction is commonly associated with type 2 diabetes mellitus and may influence glycemic control, body weight, lipid metabolism and cardiovascular risk. Because symptoms of thyroid disease may overlap with diabetes-related complaints, thyroid abnormalities may remain undiagnosed without biochemical screening. Aim of the study was to assess the prevalence and pattern of thyroid dysfunction among patients with type 2 diabetes mellitus and to study its association with selected clinical and biochemical parameters. This hospital-based observational study was conducted in the Department of General Medicine, Mamata Medical College and General Hospital, Khammam. A total of 50 patients with type 2 diabetes mellitus were included. Clinical history, duration of diabetes, body mass index, fasting blood sugar, postprandial blood sugar, HbA1c and thyroid function tests including TSH, Free T3 and Free T4 were recorded. Patients were classified as euthyroid, subclinical hypothyroid, overt hypothyroid, subclinical hyperthyroid or overt hyperthyroid. Data were expressed as frequency, percentage, mean and standard deviation. Chi-square test was used, and p-value <0.05 was considered statistically significant. Thyroid dysfunction was observed in 14 patients (28%). Subclinical hypothyroidism was the commonest abnormality, seen in 8 patients (16%), followed by overt hypothyroidism in 3 patients (6%). Thyroid dysfunction was significantly associated with female gender, increased BMI, longer duration of diabetes and poor glycemic control. Thyroid dysfunction is common among type 2 diabetes mellitus patients. Routine thyroid function screening may help in early detection and better metabolic management.
How to cite this article:
B. Nageswara Rao. Prevalence, Pattern and Clinical Correlates of Thyroid Dysfunction in Patients with Type 2 Diabetes Mellitus.
DOI: https://doi.org/10.36478/10.36478/makrjms.2007.295.301
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2007.295.301