ACE Journal of Advance Research in Chemical Sciences
ISSN: OnlineISSN: Print 2520-3703
Abstract
Diabetic foot ulcer (DFU) represent the unsafe complication of diabetes mellitus. Omentin‐1 has several functions like, anti‐inflammatory, vasodilating, anti‐hyperglycemia and modulating insulin sensitivity, which affects the brain, liver, muscle, fat as well as many other tissues, while in fasting Asprosin induced glycogenic protein hormone. Vaspin have a local and endocrine role in the progression of vascular damage in diabetic foot ulcer patients. For the assessment of Omentin‐1, Asprosin, Vaspin ,glycated hemoglobin (HbA1c) and body mass index level and to observe the correlation between parameters and study the probable relation of them with DFU in Babylon province. Omentin‐1, Asprosin, Vaspin and HbA1c were estimated in ninety subjects; 45 patients with DFU and 45 healthy persons were involved in this study. Patients and control groups with an age ranged between (35‐65) years. The level of Omentin‐1, Asprosin and Vaspin were assessed in serum by sandwich‐ELIZA kit as the method. Serum levels of Omentin‐1 displayed a significant decrease, serum Asprosin and HbA1c were significantly elevated (p<0.001) in DFU patients, while Vaspin level decreased no significantly. On the other hand, Omentin‐1 and Asprosin linked significantly with glycated hemoglobin but Asprosin don’t linked. Among diabetic foot ulcer patients in Babylon province the variability in Omentin‐1, Asprosin and Vaspin indicate the significant relationship with diabetic foot ulcer.
How to cite this article:
Sheerin H. Abbas. The Role of Omentin‐1, Vaspin and Asprosin in Sera of Patients with Diabetic Foot Ulcer in Babylon Province.
DOI: https://doi.org/10.36478/10.59218/makacejarcs.2023.2.1.5
URL: https://www.makhillpublications.co/view-article/2520-3703/10.59218/makacejarcs.2023.2.1.5