Research Journal of Pharmacology
ISSN: Online 1993-6019ISSN: Print 1815-9362
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Study and Compare Caudal Ropivacaine and Ropivacaine Plus Nalbuphine in Providing Better Post‐Operative Analgesia in Pediatric Patients
Sachin Pawar, Abdul Rahman, Dnyaneshwar Chavan, Usha Badole, Kiran Dhonnar and Nishant Shankar Padvi
Page: 4-8 | Received 29 Jan 2024, Published online: 09 Mar 2024
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Abstract
A caudal epidural block is the most common technique for regional anaesthesia among paediatric patients. Present study was aimed to compare caudal ropivacaine and ropivacaine plus Nalbuphine in providing better post‐operative analgesia in pediatric patients. Present study was prospective, double‐blinded, randomized control study conducted in patients of Age between 1 to 9 years, ASA grade 1 and 2, undergoing elective infra umbilical surgery, parents willing to participate in present study. Children were randomly divided into two groups of 30 patients, as Group A (received 0.2% Ropivacaine 1 ml/kg with 1ml NS) and Group B (received 0.2% Ropivacaine 1 ml/kg with 0.1mg/kg Nalbuphine). Mean FLACC pain score at 30min, 60 min, 90 min, 120 min, 180 min and 240 min post op were statistically highly significantly less in group B as compared to group A. Mean FLACC pain scale at 15 min, 30 min, 1 hour, 2 hours, 4 hours, 6 hours, 12 hour and 24 hours was less in group B as compared to group A and difference was statistically highly significant (p<0.001). In group A 19 (63.33%) required rescue analgesia and only 3 (10%) required rescue analgesia, difference was statistically highly significant (p<0.001). The mean Modified Bromage scale score at 30 min, 1 hour, 2 hours, 4 hour and 6 hours were comparable in group A and group B, difference was not statistically significant. (p>0.05). Nalbuphine hydrochloride in the dose of 0.1mg/kg when added as an adjuvant to 1ml/kg of 0.2% of Ropivacaine in caudal block provides prolonged duration of analgesia, however it may cause early postoperative sedation without respiratory depression as compared to the group where only Ropivacaine was used without any side effect.
How to cite this article:
Sachin Pawar, Abdul Rahman, Dnyaneshwar Chavan, Usha Badole, Kiran Dhonnar and Nishant Shankar Padvi. Study and Compare Caudal Ropivacaine and Ropivacaine Plus Nalbuphine in Providing Better Post‐Operative Analgesia in Pediatric Patients.
DOI: https://doi.org/10.36478/10.59218/makrjp.2024.1.4.8
URL: https://www.makhillpublications.co/view-article/1815-9362/10.59218/makrjp.2024.1.4.8