Research Journal of Pharmacology
ISSN: Online 1993-6019ISSN: Print 1815-9362
Abstract
The purpose of this study is to examine and correlate the link between zinc, copper, ceruloplasmin and metallothionein in healthy and HIV‐infected individuals and to evaluate the role of zinc and copper and their respective transporters in HIV‐infected individuals. The human ethics committee approved the study's procedures. Due to the lack of electronic data and the associated time and labor costs, the sample size is limited to 100 people living with HIV. The control group consists of one hundred otherwise healthy people. Metal levels in the blood were measured, along with ceruloplasmin and metallothionein concentrations. Copper, ceruloplasmin and metallothionein were all shown to be elevated in HIV‐infected individuals compared to non‐infected healthy controls. Serum copper, ceruloplasmin and metallothionein levels were significantly different between the two groups. We found that the serum zinc levels of HIV‐infected participants were much lower than those of the control group and that this difference was statistically significant. This study shows that incorrect study parameters among HIV patients can be traced back to a problem with zinc and copper absorption. This discrepancy stems from the fact that HIV patients typically have lower levels of zinc transporters compared to healthy controls.
How to cite this article:
Abhijat Kulshreshtha and Prabhakar Singh Bais. Zinc, Copper and Their Transporters Were Studied in Relation to HIV Infection Using a Case Control
Analysis.
DOI: https://doi.org/10.36478/10.59218/makrjp.2023.1.4
URL: https://www.makhillpublications.co/view-article/1815-9362/10.59218/makrjp.2023.1.4