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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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A Comparative Study of Medical Treatment with Antibiotics Alone vs Surgical Treatment with Antibiotics for Diabetic Osteomyelitis

Rohit Dubey, Rajkishore Singh, Ketan Chaturvedi and Amit P. Gujarathi
Page: 471-474 | Received 02 Mar 2024, Published online: 14 Apr 2024

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Abstract

Managing diabetic foot osteomyelitis poses a significant clinical challenge and often requires aggressive interventions, including surgical procedures. However, the optimal treatment strategy remains a topic of debate, with conservative antibiotic therapy emerging as a potential alternative. We conducted a retrospective cohort study involving diabetic patients diagnosed with foot osteomyelitis. Patients were categorized into two groups based on their treatment approach: those who received antibiotics alone (Antibiotics group) and those who underwent conservative surgery in addition to antibiotics (Surgery group). We analyzed various clinical parameters, including demographics, infection characteristics, treatment modalities and outcomes. Our study included a total of 178 patients, with 89 in each group. The average age was 63 years and majority of the patients were male. In the Antibiotics group, the average duration of antibiotic therapy was 6 weeks, while patients in the Surgery group underwent surgical intervention within an average of 10 days from diagnosis. The rate of complete healing was 65.16% in the Antibiotics group and 80.89% in the Surgery group. The median time to healing was 11 weeks in the Antibiotics group compared to 9 weeks in the Surgery group. Complications such as wound dehiscence occurred in 14.61% of the Antibiotics group and 7.87% of the Surgery group. Our findings suggest that combining conservative surgery with antibiotics may lead to faster healing and lower complication rates compared to antibiotic therapy alone for diabetic foot osteomyelitis. However, further prospective studies are necessary to validate these results and provide guidance for clinical decision‐making.


How to cite this article:

Rohit Dubey, Rajkishore Singh, Ketan Chaturvedi and Amit P. Gujarathi. A Comparative Study of Medical Treatment with Antibiotics Alone vs Surgical Treatment with Antibiotics for Diabetic Osteomyelitis.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.4.471.474
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.4.471.474