Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Comparative Study of the Effect of the Endotracheal Infra Cuff Alkalinized Lidocaine and Saline in Reducing the Incidence of Emergence Coughing, Post Operative Sore Throat and Hoarseness: A Randomized Clinical Trial
Krishna Chaitanya Bevara, Radha Gupta, Sukirti Prakash and Swaran Bhalla
Page: 441-452 | Received 25 Jan 2024, Published online: 04 Apr 2024
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Abstract
The gold standard of airway management and usage of the cuffed ETT is routine in day to day practice. Adequate ventilation is provided by ETT and risk of aspiration is less. The usage of Nitrous oxide along with Oxygen during maintenance leads to elevation of cuff pressure as Nitrous oxide diffuses inside the cuff. Alkalinized Lidocaine is more permeable and has a local anaesthetic property which blocks the tracheal nociceptive receptors thereby the incidence of sore throat, emergence coughing and hoarseness. To evaluate and compare the effects of endotracheal tube cuff inflation media, with alkalinized 2% Lidocaine and Saline on emergence coughing, postoperative sore throat and hoarseness of voice during N2O maintained general anaesthesia. Seventy patients divided into 2 groups (n=35) were randomly allocated between 18‐60 years of age who were posted for elective surgery under general anaesthesia with endotracheal intubation. The ETT cuff was inflated with alkalinized Lidocaine in the group I and normal Saline in group ‐II. Both the groups were compared regarding postoperative sore throat, emergence coughing and hoarseness at time intervals of 30, 60, 90 min and 24 hours. post‐extubation, along with haemodynamic variations. The quantitative variables are compared across groups using unpaired t‐test and while across follow‐up comparison is done using paired t‐test. Qualitative variables are expressed as frequencies/percentages and assessed using chi‐square Exact test. A p<0.05 is considered statistically significant. The data is entered in MS Excel spread sheet and statistical analysis performed using IBM SPSS version 20.0 software. The variables are summarized using frequency distribution and mean±sd. The demographic data and duration of surgery were comparable between the 2 groups. The haemodynamic variations were less significant in the alkalinized Lidocaine group compared to the group of normal Saline. The incidence of a postoperative sore throat (POST), cough (C), hoarseness of voice (H) and coughing/bucking is significantly lesser in Group I as compared to Group II. The severity of the POST, cough and hoarseness of voice is least in Group I compared to Group II. Our study concludes that inflation of ETT cuff with alkalinized Lidocaine reduces the incidence of postoperative sore throat, emergence coughing and hoarseness of voice compared to inflation of ETT cuff with normal saline.
How to cite this article:
Krishna Chaitanya Bevara, Radha Gupta, Sukirti Prakash and Swaran Bhalla. Comparative Study of the Effect of the Endotracheal Infra Cuff Alkalinized Lidocaine and Saline in Reducing the Incidence of Emergence Coughing, Post Operative Sore Throat and Hoarseness: A Randomized Clinical Trial.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.4.441.452
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.4.441.452