Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Dystonia is a movement disorder characterised by sustained muscle contraction, frequently causing twisting and repetitive movement or abnormal posture. Tremors occur commonly with dystonia and either involve affected body parts (dystonic tremors) or other body parts not affected by dystonia (tremor associated with dystonias). Dystonia is often aggravated by voluntary movement. The underlying neurochemistry of dystonia is not known but dopaminergic, cholinergic and glutaminergic neurotransmitter systems may be involved. Efforts are ongoing to develop a practical, reliable and validated screening tool for dystonia that can be applied to large populations. The study was conducted at a tertiary care hospital. 18 patients over 12 years of age presenting to neurology OPD with diagnosis of focaldystonias and dyskinesias (cervical dystonia, blepharospasm, hemifacial spasm, writer’s cramps, any others). Genetic testing for Huntington for selected patients who have a positive family history and a combination of movement disorders with psychiatric symptoms, will be done. Baseline severity of dystonia will be assessed at point of diagnosis using visual analogue scale. Data will be recorded and analyzed. Age of patients ranged from 12 years to 68years, with the mean age being 46 years. 18 patients, 38.9% had hemifacial spasm,16.7% had blepharospasm, 22.2% had cervical dystonias, 5.6% had facial dystonia, 16.7% had jaw opening dystonias and5.6% had hemidystonias. out of 18 patients 2 had sensory tricks. 5.6% had neurological (hemiplegia) additional finding and 12.2% had systemic (polio leg, KF ring) additional finding. Stressors were present in 50% of patients, seen in 5/7 patients with hemifacial spasm, 2/4 patients with cervical dystonia and 1/3 patients with blepharospasm. Sensory tricks were used for relieving of symptoms by 1 patient each of cervical dystonia and blepharospasm.
How to cite this article:
Uma Sundar and Pingala Aalane. Study to Evaluate the Spectrum of Adult Onset Focal Dystonias and Dyskineasis Presenting in Neurology OPD in a Tertiary Care Hospital.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.3.187.191
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.3.187.191