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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Study of Regression of Left Ventricular Hypertrophy with Angiotensin Converting Enzyme Inhibitors in Patients of Hypertension

Pentapalli Krishna Kusuma, Kosuri Satya Anand, Singampalli Pavani Dedeepya, Padala Sai Krishna Nanda Kumar Reddy, Chekuri Krishna Sri Kavya and Mogalla Yogi Venkata Sai
Page: 251-256 | Received 22 Dec 2023, Published online: 23 Jan 2024

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https://doi.org/10.36478/10.59218/makrjms.2024.2.251.256

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Abstract

Hypertension is a leading cause of morbidity and mortality globally, often associated with cardiovascular diseases (CVDs). Left ventricular hypertrophy (LVH) is a preclinical cardiac condition linked to hypertension. This study aimed to assess the effects of Enalapril, an ACE inhibitor, on left ventricular parameters and other related factors in hypertensive patients. The study included patients with hypertension and LVH, measuring various cardiovascular parameters before and after Enalapril treatment. Parameters assessed included left ventricular mass (LVM), left ventricular internal diameter (LVID), posterior wall thickness (PWT) and interventricular septal thickness (IVST). Additionally, age and gender distributions of hypertensive patients were analyzed. Enalapril treatment led to a significant reduction in LVM, PWT, IVST, systolic blood pressure and diastolic blood pressure. The study also found that hypertension was more prevalent in males and increased with age. ECG criteria for LVH demonstrated lower sensitivity compared to 2D echocardiography. Enalapril treatment resulted in favorable changes in left ventricular parameters and blood pressure, highlighting its effectiveness in managing hypertension and associated cardiac conditions. The study emphasizes the importance of ACE inhibitors in controlling hypertension and preventing cardiovascular complications.

How to cite this article:

Pentapalli Krishna Kusuma, Kosuri Satya Anand, Singampalli Pavani Dedeepya, Padala Sai Krishna Nanda Kumar Reddy, Chekuri Krishna Sri Kavya and Mogalla Yogi Venkata Sai. Study of Regression of Left Ventricular Hypertrophy with Angiotensin Converting Enzyme Inhibitors in Patients of Hypertension.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.2.251.256
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.2.251.256