Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Dengue fever, caused by the dengue virus, is a significant global health concern. This study aimed to analyze the clinical and laboratory characteristics of dengue fever patients at a tertiary hospital to understand the disease’s progression and severity. This retrospective study included 70 patients diagnosed with dengue fever at Department of General Medicine, Mallareddy Women’s Medical College, Hyderabad, from January 2022 to December 2022. Data on demographic information, clinical symptoms, and laboratory findings were collected. Patients were classified into three severity groups Dengue Fever (DF), Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS). Descriptive statistics mean±standard deviation (SD) and p‐values were calculated. The study population had an average age of 35.2 years, with a male predominance (57.1%). Clinical symptoms include fever, headache, rash, myalgia and arthralgia. Laboratory findings showed a trend towards lower hemoglobin levels, lower platelet counts and lower serum albumin levels with increasing severity from DF to DHF to DSS. The mean hemoglobin level was 13.2 g dL-1 (SD = 1.5) and the mean platelet count was 150 x10^9 L-1 (SD = 45). Serum albumin levels were lower in DHF and DSS groups compared to DF. This study highlighted significant clinical and laboratory differences among dengue fever patients based on disease severity. The findings underscore the importance of vigilant monitoring of hematological and biochemical parameters in dengue patients for early recognition and management of severe cases. These insights can aid in improving patient care and guiding future research in dengue fever.
How to cite this article:
Madhavaram Niteesh Rao and Katragadda Nithin. Comprehensive Clinical and Laboratory Characterization of Dengue Fever Patients at a Tertiary Hospital: A Retrospective Analysis.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.2.247.250
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.2.247.250