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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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A Prospective Study of Analgesic Results of Intravenous Dexmedetomidine in Patients Undergoing Meshplasty for Inguinal Hernia Repair under Spinal Anaesthesia

Sulakshna Tripathi, Ajay Kumar Sinha, Rajesh Verma and Suvarna Prasad
Page: 195-200 | Received 20 Dec 2023, Published online: 20 Jan 2024

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https://doi.org/10.36478/10.59218/makrjms.2024.2.195.200

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Abstract

This research work was designed to study the sedative and analgesic effect following the administration of intravenous dexmedetomidine as an adjuvant to intrathecal hyperbaric bupivacaine. Patients having any contraindications to spinal anaesthesia (i.e. inability to maintain stillness during needle puncture, raised intracranial pressure, skin/soft tissue infection at the site of needle puncture, severe hypovolemia, coagulopathy, preexisting neurological disease), known allergy to study drug, heart block/dysrhythmia and patients on treatment with a‐adrenergic antagonists were not included in the study. The average baseline values of haemodynamic data for both groups were statistically similar. The number of patients who experienced low blood pressure and slow heart rate was not significantly different between the two groups (p = 0.139 and p = 0.128, respectively). The infusions were continued throughout episodes of low blood pressure and slow heart rate and the intensity of these effects did not justify stopping the infusions at any time. Patients in group A showed a noticeably higher sedation score compared to those in group B (p< 0.001). The level of sedation was superior in the dexmedetomidine group compared to the placebo group. The occurrence of bradycardia was much greater in the dexmedetomidine group, but it was temporary and could be reversed by atropine.

How to cite this article:

Sulakshna Tripathi, Ajay Kumar Sinha, Rajesh Verma and Suvarna Prasad. A Prospective Study of Analgesic Results of Intravenous Dexmedetomidine in Patients Undergoing Meshplasty for Inguinal Hernia Repair under Spinal Anaesthesia.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.2.195.200
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.2.195.200