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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Clinico-Therapeutic Analysis of Posterior Urethral Valve in Children: A Hospital Based Retrospective Study from Eastern India

Imran Khan, Anindya Pradhan, Indrani Ghosh, Indranil Chatterjee and Aritra Kapat
Page: 593-598 | Received 24 May 2024, Published online: 23 Jun 2024

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https://doi.org/10.36478/10.59218/makrjms.2024.2.18.593.598

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Abstract

Management of posterior urethral valve (PUV) is a challenge to pediatric surgeons due to its late presentation and sequlae despite optimum treatment, which needs a long term follow-up. The aim of the study is to describe the presentation, therapeutic management and eventual outcome in cases of posterior urethral valve. It is a hospital-bound time-framed retrospective analysis based on digitalized hospital records of the past 10 years, which included postoperative PUV patients. A total of 40 cases were analyzed. 7.5% of cases were antenatally detected. The mean age of presentation was 8.92±6.27 months. The major presenting symptom was post micturition dribbling, followed by poor urinary stream. 30% of cases needed medical management with alpha blockers. Repetitive urethral valve fulgration was required for 27.5% of the patients, whereas 25% patients needed draining procedures. Vesicostomy was done in 17.5% cases and ureterostomy was done in 7.5% cases. Postoperatively, there was significant improvement in vesicoureteric reflux, with 82.5% of patients showing no signs of reflux. 75% of patients had creatinine more than 1 mg dL‾1 preoperatively and postoperative change in serum creatinine was statistically insignificant (F2,117 = 2.50, p = 0.086). The structural ultrasonographic bladder parameters also didn’t change significantly postoperatively; rather, they decreased gradually on long-term follow-up. A timely evaluation and apt management are required for cases of PUV. Despite optimum management, the disease imparts some long-standing deleterious effects on the bladder and kidney, which often lead to end-stage renal diseases, which prompt regular, periodic follow-up.

How to cite this article:

Imran Khan, Anindya Pradhan, Indrani Ghosh, Indranil Chatterjee and Aritra Kapat. Clinico-Therapeutic Analysis of Posterior Urethral Valve in Children: A Hospital Based Retrospective Study from Eastern India.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.2.18.593.598
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.2.18.593.598