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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Liver Function and Platelet Count as an Early Correlate of Delirium Tremens in Patients of Alcohol Dependence Syndrome Admitted in Rehabilitative Care Center

Sunil Kumar Giriyappa Patil, Neha V. Mattikoppa, Khushboo Dewani, G.S. Harshitha, Mahesh R. Gowda and M.T. Sathyanarayana
Page: 255-258 | Received 29 Nov 2023, Published online: 16 Jan 2024

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https://doi.org/10.36478/10.59218/makrjms.2024.1.255.258

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Abstract

The utility of several laboratory parameters as possible risk factors/predictors for severe AWS has also been investigated. It is extremely important for clinicians to be able to identify individuals at high risk for developing a severe AWS. The study was conducted in tertiary psychiatry center. The first group consists of simple withdrawal and the second group consists of complicated withdrawal with delirium. Socio‐demographic details were collected using a semi‐structured proforma, results of basic biochemical tests including platelet count and liver function tests (Total Bilirubin, Direct Bilirubin, Indirect Bilirubin, AST, ALT, AST//ALT ratio, GGT) which were performed as a routine in the management of alcohol withdrawal were collected for the study. A total of 402 patients were included in the study. Nearly 26.1% of patients had thrombocytopenia. 43.58% of patients with thrombocytopenia had delirium. 38.3% of patients had total bilirubin more than 1.3 mg/dl of which 44.44% had delirium. About 66.7% of patients had SGOT more than 40IU. 61.5% of patients with higher SGOT levels had delirium. 85.8% of patients had GGT more than 32IU and 87.17% of them had delirium. Platelet counts were significantly lower in patients with delirium/altered sensorium (p = 0.00). Further studies can try to elaborate the evidence with larger sample sizes and can also try to assess if these parameters have any role in precipitation of alcohol withdrawal into Wernicke's encephalopathy and Korsakoff’s psychosis.

How to cite this article:

Sunil Kumar Giriyappa Patil, Neha V. Mattikoppa, Khushboo Dewani, G.S. Harshitha, Mahesh R. Gowda and M.T. Sathyanarayana. Liver Function and Platelet Count as an Early Correlate of Delirium Tremens in Patients of Alcohol Dependence Syndrome Admitted in Rehabilitative Care Center.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.1.255.258
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.1.255.258