Physiological jaundice is frequently encountered in the newborn period. Almost all newborn infants have a serum or plasma total bilirubin (TB) level >1 mg dL‐1 in contrast to normal adults in whom the normal TB level is <1 mg dL‐1. In our study newborns requiring phototherapy and newborns not requiring phototherapy were taken into study. A total of 150 babies were considered in the study, of which 68 babies were excluded from the study. Eighty two babies were included in the study. The babies were divided into study group (N = 41) and Controls (N = 41). Socio‐economic and demographic data were collected for all babies. Mean serum total bilirubin levels in study group‐14.3 mg dL‐1, Control group‐ 13.2 mg dL‐1. Mean serum Vitamin D levels in study group‐15.48 mg dL‐1, Control group‐19.92 mg dL‐1. Risk factors for Neonatal Hyperbilirubinemia like prematurity, Rh incompatibility, ABO incompatibility, dehydration were excluded. There is significant difference between the two groups in terms of Vitamin D levels (p = 0.02). In our study, we found that total bilirubin levels has weak negative correlation with serum Vitamin D levels which is not statistically significant. (p = 0.3 ,r = 0.1 ). However it was found that serum direct bilirubin has a significant relation with serum Vitamin D. There is no significant association between indirect hyperbilirubinaemia and serum vitamin D levels in new borns with jaundice at a level necessitating phototherapy. We conclude that our study needs to be verified by future research.
Vishal Balagouda Patil, R. B. Sahana, Shivaleela and Jayaraj Harsoor. A Prospective Study of Vitamin D Levels in Term Neonates with Jaundice Requiring Phototherapy.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.1.208.211
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.1.208.211