Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
To assess the possible causes, clinical findings, associated co‐morbidities, investigations, treatment modalities and the clinical outcomes of post covid‐19 rhino‐cerebral mucormycosis. A sum total of thirty‐three patients presenting with symptoms and signs of Rhinocereberal Mucormycosis in the Department of E.N.T and H and N.S. Department, BRIMS, Bidar from May 2021 to April 2022, were included in the study. These patients were subjected to radiological investigations like MRI and CT scan of Paranasal sinuses and brain. All these patients underwent surgical debridement and systemic antifungal therapy. The clinical course, management, outcome data were recorded. Out of 33 patients, there were 28 (84.8%) males and 5 (15.2 %) were females. All the patients were categorised according to their age. Four patients were in the age group of 21‐30 years, 10 patents in the age group of 31‐40 years, 07 patients each in the age group of 41‐50 years and 51‐60 years and 5 patients were in the age group of 61‐70 years. The p‐value was significant (p<0.05). Micro‐organisms isolated were mucor in 22 patients, aspergillus in 04, Rhizopus in 03 and others in 04 cases. Previous history of O2 therapy was present in 9 patients, no history of O2 therapy in 20 and in 4 cases the history of O2 therapy was not known. History of receiving steroid therapy was observed in 19 patients, no history of steroid therapy was seen in 10 patients and 4 patients had no information about the steroid therapy. Thirty patients were Covid positive, 09 patients were Covid recovered, 8 patients were non‐covid and covid status was unknown in 03 cases. The complications like visual impairment were observed in 05 cases and hemiparesis/hemiplegia in 03 cases. Surgical debridement was done in 31 patients. All the patients received Inj. Amphotericin‐B[liposomal] for 2 weeks followed by Tab. Posoconazole 300mg for 4 weeks. The p value was significant (p<0.05). Mucormycosis is a rapidly progressing disease and can prove fatal. The early diagnosis and treatment can prevent complications and save lives.
How to cite this article:
Malige Rajkamal, Parmeshwarappa K. Dhanurkar and Sumanth Kanjikar. A Clinical Study of Mucormycosis in a Tertiary Care Center.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.1.199.202
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.1.199.202