Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Malaria remains a major public health problem and leading cause of mortality in tropical countries. A variety of hematological alterations like anemia, leukocytosis or leukopenia, thrombocytopenia and rarely DIC have been reported in malaria. The present study aimed to evaluate the alteration of hematological parameters in malaria and their probability to detect malaria in acute febrile illness cases. This was case‐control study, conducted in the department of the medicine, ESIC Medical College and Hospital, Hyderabad for one year duration. 50 diagnosed cases of malaria as cases and 50 acute febrile illness malaria negative patients as control were enrolled and analysed. Diagnosis of malaria was made by peripheral blood smear. Clinical presentation and hematological parameters were studied in all of them. Out of total malaria cases 52% were infected with Plasmodium vivax (PV) and 48% was of Plasmodium falciparum (PF). Majority of the malaria cases (76%) were 18‐30 years of age, predominantly male. Mean age±SD among cases was 25.98±10.19 years. Among clinical presentation, most of the participants (74% cases and 66% control) were observed continuous fever. Splenomegaly was found in 60% of malaria cases and only 8% of non malaria control this was statistically significant (p<0.05). There was a statistically significant difference in hemoglobin, platelet counts, total leucocyte count and RDW (p<0.001) levels in patients with malaria compared to patients without the disease. Anemia and thrombocytopenia was the most common hematological changes. They can be helpful in detecting early complications to monitor and treat them effectively. Malaria, P. vivax, P. falciparum, fever, thrombocytopenia, hematological changes.
How to cite this article:
Rajesh Ambati, Srikanth Naredu, G. Ramaiah, Chennakesavulu Dara and Naresh . Haematological Predictors of Malaria in Acute Febrile Illness.
DOI: https://doi.org/10.36478/10.59218/makrjms.2024.1.138.143
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2024.1.138.143