Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Severe burn is the leading cause mortality because of the higher metabolic and physiological abnormalities Hypoalbuminemia is a common clinical deficiency in burn patients and is associated with complications related to increased extravascular fluid, including edema, abnormal healing and susceptibility to sepsis. This study aimed to find whether serum albumin, globulin, total protein, cholesterol and triglyceride levels are clinically relevant to determine the mortality of a burn patient and thereby the patient’s outcome. This cross-sectional observational was conducted in the in the Department of Surgery in collaboration with Department of Biochemistry, in a tertiary care hospital, central India. All patients who were admitted to the burn unit during the study period were enrolled in our study. detailed history and clinical examination were recorded. Serum albumin, globulin, total proteins and serum cholesterol were estimated on alternate days starting from day of admission till discharge or death. Out of total 255 burn patients, 208 (81.6%) were survivors and 47 (18.4%) patients expired during the course of treatment. Majority of the patients was female (56.9%), second grade burn cases were 54.5%, most of them were thermal burn (84.3%). Sepsis was the most common (34.1%) complication in burn patients. Majority of patients showed an involvement of 31-40% TBSA with 45.2% of survivor patients, whereas among non survivor 51-60% TBSA in 61.7% cases. Serum albumin, globulin, total serum protein and scrum cholesterol significantly associated with the mortality of burn patients. The increase in values of albumin, globulin, total protein and cholesterol during the clinical course reduces mortality with serum albumin acting as the best predictor and cholesterol the least.
How to cite this article:
Vidyanand Pandit, Soobia Karim Ansari and Dharmveer Sharma. Significance of Serum Proteins and Serum Lipids as a Prognostic Mortality Indicator in Burn Patients.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.9.88.92
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.9.88.92