Surgical site infections (SSIs) pose a significant healthcare challenge with implications for patient outcomes and healthcare costs. This observational study investigates the influence of postoperative antibiotic prophylaxis on the incidence of SSIs, recognizing the importance of evidence-based infection prevention in surgical practice. A diverse cohort of 100 patients undergoing various surgical procedures, including appendectomy (30%), cholecystectomy (25%) and orthopedic surgeries (15%), was included in the study. Demographic data, surgical details and antibiotic prophylaxis information were collected. Patients were categorized into those who received appropriate antibiotic prophylaxis (70%) and those who did not (30%). SSIs were monitored postoperatively. Statistical analysis, including chi-squared tests, was employed to assess the association between antibiotic prophylaxis and SSIs. In a study involving 100 diverse surgical patients, we found that 70% received appropriate antibiotic prophylaxis, while 30% did not due to various factors. Incidence of surgical site infections (SSIs) was significantly lower in the group with proper prophylaxis (8.6%) compared to those without (40%). This underscores the protective role of appropriate antibiotic prophylaxis against SSIs. This observational study reveals a substantial association between proper antibiotic prophylaxis and reduced SSIs. Patients who received appropriate prophylaxis experienced a significantly lower risk of developing SSIs compared to those who did not. These findings emphasize the critical role of evidence-based antibiotic prophylaxis in surgical infection prevention. Tailoring prophylaxis strategies to specific patient populations and surgical procedures is imperative. These results contribute to the ongoing efforts to enhance patient care and minimize the burden of SSIs in surgical practice, highlighting the importance of adhering to infection prevention guidelines.
Pala Anand Kumar and Yarra Sudhakar. Postoperative Antibiotic Prophylaxis and the Incidence of Surgical Site Infections: An Observational Study.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.9.34.37
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.9.34.37