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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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The Role of Adherence to Antidiabetic Medications in Blood Pressure Control among Diabetic Hypertensive Patients: A Longitudinal Cohort Analysis

S. V. Keshavanath, B.A. Sai Kishore and Kanukurthi Deepika
Page: 1-5 | Received 19 Jun 2023, Accepted 14 Jul 2023, Published online: 31 Jul 2023

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https://doi.org/10.36478/10.59218/makrjms.2023.9.1.5

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Abstract

Adherence to antidiabetic medications is crucial for blood pressure control in diabetic hypertensive patients. However, the longitudinal impact of such adherence on blood pressure and cardiovascular events remains to be explored. To compare blood pressure control and incident cardiovascular events over an 18‐month period between diabetic hypertensive patients adhering to antidiabetic medications and those who do not. A cohort of 100 diabetic hypertensive patients was categorized into two groups: Adherent (n = 55; took >80% of their prescribed doses) and Non‐adherent (n = 45; took <80% of their prescribed doses). Baseline demographics, blood pressure measurements at 6, 12 and 18 months and incident cardiovascular events were recorded. Baseline Characteristics: Adherent Group: Mean age 62±10 years, 40% females, initial blood pressure 150/90 mmHg. Non‐adherent Group: Mean age 63±9 years, 42% females, initial blood pressure 151/91 mmHg. Blood Pressure Over Time: 6 months: Adherent Group 135/85 mmHg vs. Non‐adherent Group 148/88 mmHg. 12 months: Adherent Group 130/80 mmHg vs. Non‐adherent Group 147/89 mmHg. 18 months: Adherent Group 128/78 mmHg vs. Non‐adherent Group 146/90 mmHg. Between‐ Group Differences: Significant blood pressure reduction in the Adherent Group compared to the Non‐adherent Group by 18 months (p<0.001 for both systolic and diastolic pressures). Incident Cardiovascular Events: Adherent Group: 3.6% (2 out of 55 individuals). Non‐adherent Group: 17.8% (8 out of 45 individuals). Adherence to antidiabetic medications significantly influences blood pressure control in diabetic hypertensive patients over 18 months. Non‐adherence is associated with a higher rate of cardiovascular events, underscoring the importance of medication adherence for broader cardiovascular health.

How to cite this article:

S. V. Keshavanath, B.A. Sai Kishore and Kanukurthi Deepika. The Role of Adherence to Antidiabetic Medications in Blood Pressure Control among Diabetic Hypertensive Patients: A Longitudinal Cohort Analysis.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.9.1.5
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.9.1.5