Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Leprosy, a chronic infectious disease caused by Mycobacterium leprae, continues to pose a substantial public health challenge globally. Despite significant progress, leprosy remains prevalent in certain regions, with India accounting for a significant portion of the burden. This study delves into the less‐explored realm of renal involvement in leprosy an enduring global health challenge caused by Mycobacterium leprae. Despite being primarily recognized for skin and nerve effects, leprosy can also impact the kidneys, leading to diverse clinical indicators like proteinuria, hematuria, altered blood parameters and reduced glomerular filtration rate. Histopathological analysis reveals various renal lesions such as glomerulonephritis, nephrosclerosis and tubulointerstitial nephritis often observed during reactive phases and within the lepromatous spectrum of the disease. While the direct invasion of renal tissue is not proven, these findings emphasize the importance of holistic patient care, early diagnosis and tailored treatment. Recognizing the interplay between leprosy and renal function contributes to enhanced patient management and informs comprehensive public health strategies for tackling leprosy’s global impact.
How to cite this article:
Shashank Pandey, Sunil Agarwal, Alpana Raizada, Seema Negi and Abha Sharma. Leprosy‐Associated Renal Involvement: Clinical Manifestations and Histopathological Insights.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.784.791
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.784.791