Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
Gestational diabetes mellitus (GDM) poses significant health risks to both mothers and babies, arising from insulin resistance linked to oxidative stress caused by excess iron. The aim of this study was to compare hemoglobin and packed cell volume (PCV) levels in pregnant women with and without GDM, as these parameters reflect body iron status. Understanding the association between hemoglobin, PCV and GDM can contribute to improved management and prevention strategies for this condition during pregnancy. In a case‐control study conducted at a tertiary care center in Central India, 100 cases and 100 controls were included. The cases consisted of pregnant women diagnosed with GDM according to the guidelines set by the American Diabetes Association (ADA), during the gestational period of 24‐28 weeks. The control group consisted of pregnant women without GDM at the same gestational age. Data collection involved the use of a validated questionnaire. All participants received iron supplementation based on the national program. Hemoglobin and PCV levels were measured using a 2 mL blood sample obtained through venepuncture and analyzed using an automated analyzer. The association between elevated hemoglobin and PCV levels and the risk of developing GDM was assessed using Chi‐square analysis, with a significance level of p<0.05. A notable distinction was observed in hemoglobin levels between the cases and controls, indicating a statistically significant difference. Additionally, the cases exhibited significantly higher packed cell volume (PCV) values compared to the controls. The study identified a statistically significant correlation between elevated maternal hemoglobin levels and PCV with GDM.
How to cite this article:
Sonu Kumar Batham, Archana Kori, Abhinav Junwal and Manisha Chauhan. Hemoglobin and Packed Cell Volume in Gestational Diabetes Mellitus: A Case Control study.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.78.82
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.78.82