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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Analysis of Dosimetric Differences between Two High Dose Rate Brachytherapy Sources in Intracavitary Applications: An Institutional Experience

N. Shashikala, B. Shwetha, B. Rekha Reddy, S. Sathiyan and K. M. Ganesh
Page: 684-689 | Received 06 Jul 2023, Published online: 03 Aug 2023

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https://doi.org/10.36478/10.59218/makrjms.2023.684.689

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Abstract

This study aimed to compare and evaluate the intracavitary treatment plans performed using two different treatment planning systems one incorporating Ir‐192 source and the other Co‐60 source. 50 computed tomography (CT) based intracavitary brachytherapy treatments, planned in SagiPlan and BrachyVision treatment planning systems were analyzed. For each patient planned in Sagiplan, a comparative plan was generated in BrachyVision maintaining the same dwell positions and dose to point A. The treatment plans were compared based on the clinical parameters such as D90, D50 for HRCTV and dose to 0.1 cc, 1 cc and 2 cc of OARs namely bladder, rectum and sigmoid. Percentage difference of 1.95 and ‐0.79% was seen in the D90 and D50 values of HRCTV between Ir‐192 and Co‐60 radioisotopes. Statistically significant differences of 9.43, 8.02 and 9.0% was observed respectively in the 0.1 cc, 1 cc and 2 cc volumes of sigmoid. Also mean percentage difference of 0.95, 3.0 and 5.31% was seen in D0.1cc, D1cc and D2cc of rectum. Further D0.1cc, D1cc and D2cc values of bladder were ‐3.04, ‐2.12 and 2.4%, respectively. No significant difference was observed in the volumes encompassed by 50, 100, 150 and 200% isodose volumes between the two radioisotopes. The treatment time was approximately 1.2 times higher with Co‐60 as compared to Ir‐192. The dosimetric parameters analyzed for Co‐60 and Ir‐192 sources showed comparable results. Significant differences between the two sources were observed in the doses to sigmoid which could be due to the bulge in the isodose lines of Co‐60 source along the longitudinal axis. These differences could be eliminated with appropriate techniques of optimization in the actual treatment plan.

How to cite this article:

N. Shashikala, B. Shwetha, B. Rekha Reddy, S. Sathiyan and K. M. Ganesh. Analysis of Dosimetric Differences between Two High Dose Rate Brachytherapy Sources in Intracavitary Applications: An Institutional Experience.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.684.689
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.684.689