Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
There are 390 million dengue infections per year, making them one of the arboviral illnesses that are now spreading the fastest. Particularly in developing nations, they significantly increase morbidity and death, placing a heavy economic burden on those nations. To evaluate the function of the NS1 antigen Assay in the delivery of pediatric dengue treatment. Prospective, observational cross‐sectional research was used in the current study. The Surat Municipal Institute of Medical Education and Research's pediatric department conducted this study from January 2021 to December 2022. Within three days of the illness, 79 (63.2%) of the youngsters tested positive for the NS1 Antigen. Ns1 antigen tests were positive in 46 children (36.2%) who had been unwell for 4 to 5 days. Primary dengue fever struck 61 (48.8%) of the 125 children, whereas secondary dengue fever struck 64 (51.2%). Mild dengue was identified in 13 (27.0%) children with titre values between 9 and 11, 16 (35.4%) children with titre levels below 9, and 19 (38.8%) children with titre levels above 11. Tissue titres were as low as 9, as high as 11, and as low as >11 in 8 of the children with severe dengue. Children with severe dengue had titre levels as low as nine in three (23.1%), two (15.4%), and eight (61.5%) cases. The p value of 0.3637 indicated that it was not statistically significant. Our findings suggest that further research is needed to establish early detection tools for dengue fever, and that NS1 Antigen ELISA titres may not be useful in predicting the severity of dengue fever in children.
How to cite this article:
Shreya Ashwin Bhatt. Association of the Severity of Dengue Fever with Ns1 Antigen Titres in Children.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.626.629
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.626.629