Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Bacterial infections pose a significant threat to public health, especially with the emergence of antibiotic resistance. Understanding the intricate interactions between bacterial resistance and host virulence is crucial for devising effective strategies to combat infections. The host employs various defence mechanisms, including the expression of antimicrobial peptides and the activation of signalling pathways, to protect against bacterial invasion. However, bacterial pathogenicity remains a significant challenge, hindering the development of new drugs and vaccines. Bacterial pathogenesis involves exposure, adhesion, invasion, infection and transmission and is influenced by virulence factors encoded in bacterial DNA. The rise of multiple drug resistance (MDR) highlights the urgency of exploring alternative treatment options. Ozone therapy has demonstrated potent antibacterial properties and has been studied against various bacterial strains, offering a potential safer and more economical alternative to conventional antibiotics. Ozone's mechanism of action primarily involves oxidative stress on pathogens, leaving healthy cells relatively unharmed. This targeted approach may reduce adverse effects and help combat antimicrobial resistance. However, further research and clinical trials are necessary to validate its efficacy and safety
How to cite this article:
Marshalein Anthony, M. Satyalakshmi, D. Sathyanath, P. Yuvaraj Paul and Shrikanth Muralidharan. Efficacy of Ozone Therapy as an Antibacterial Agent: A Narrative Review.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.455.462
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.455.462