Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
The prevalence of diabetes has led to its recognition as a significant global health issue due to its numerous detrimental impacts on ocular tissue. The objective of this study is to examine the impact of diabetes on corneal thickness, specifically in relation to the duration of the disease and the level of glycosylated haemoglobin. A case‐control study was conducted at a tertiary eye care centre in central India from May 2019 to April 2020. The study included a total of 200 patients, with 100 individuals diagnosed with type 2 diabetes and 100 individuals without diabetes. In addition to conducting a comprehensive ophthalmic examination, an assessment of the central corneal thickness (CCT) was performed for each eye using an ultrasound pachymeter. A blood analysis was conducted to assess the HbA1c concentration in individuals with diabetes. The average central corneal thickness (CCT) in individuals with diabetes was found to be 564.541±24.56 μ, while in those without diabetes it was 519.453±25.98 μ. The observed difference between the two groups was determined to be clinically significant (p<0.002). The average duration of diabetes was 9.478±1.7 years. The central corneal thickness (CCT) was observed to be greater in individuals with diabetes who had a duration of more than 10 years compared to those with a duration of less than 10 years (p = 0.115). Similarly, the CCT was found to be higher in individuals with a HbA1c level greater than 6.5% compared to those with a HbA1c level less than 6.5% (p = 0.231). However, it is important to note that these differences did not reach statistical significance. There is a notable disparity in corneal thickness between individuals with diabetes and those without the condition. The assessment of central corneal thickness (CCT) is essential in the evaluation of diabetic patients to determine the functional condition of the thickened cornea, as there exists a clear correlation between CCT and diabetes.
How to cite this article:
Shoaib Arshad, Madhubala Gubrele, Bimalesh Ojha, Pankaj Kataria and Souryakant Varandani. Relationship Between Central Corneal Thickness and Type 2 Diabetes: A Case Control Study.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.389.393
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.389.393