Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
The evaluation of sentinel lymph nodes (SLNs) plays a crucial role in the management and prognosis of breast carcinoma. This study aimed to investigate the utility of frozen section evaluation in assessing SLNs and its clinicopathological correlation in breast carcinoma patients. A retrospective analysis was conducted on a cohort of breast carcinoma patients who underwent SLN biopsy and frozen section evaluation. The frozen sections were evaluated for the presence of metastatic deposits and the results were compared with the final histopathological examination of the SLNs. The utility of frozen section evaluation in assessing sentinel lymph nodes (SLNs) based on the final histopathology results. The table indicates a significant association between frozen section evaluation and final histopathology, highlighting the value of frozen section evaluation in assessing SLNs. The concordance between frozen section evaluation and the final histopathological examination of SLNs regarding the presence or absence of metastatic deposits. The significant association between frozen section evaluation and metastatic deposits suggests the reliability of frozen section evaluation in detecting metastasis in SLNs. The clinicopathological parameters associated with SLN involvement. The significant correlations observed between Tumor Size, Histological Grade, Hormone Receptor Status, Lymphovascular Invasion and SLN involvement emphasize the importance of these parameters in predicting SLN involvement in breast carcinoma patients. These findings contribute to clinical decision‐making and management strategies for patients with breast carcinoma. Frozen section evaluation of SLNs in breast carcinoma provides valuable intraoperative information for immediate decision‐making regarding axillary lymph node dissection. It demonstrates high accuracy in detecting metastatic involvement of SLNs. The clinicopathological correlation of frozen section results with various tumor characteristics helps in better understanding the disease progression and optimizing patient management. Further prospective studies are warranted to validate these findings and refine the clinical application of frozen section evaluation in breast carcinoma.
How to cite this article:
Mohd. Ghouse Mohiddin, Asiya Tabassum, Maryam Fatima and T. S. Shamshuddeen. Frozen Section Evaluation and Clinicopathological Correlation of Sentinel Lymph Nodes in Breast
Carcinoma.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.302.306
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.302.306