Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
Breast lumps are a common concern among women and their accurate diagnosis is crucial for appropriate management. Fine needle aspiration cytology (FNAC) and histopathology are two diagnostic techniques commonly used in the evaluation of breast lumps. This study aimed to compare the diagnostic accuracy of FNAC with histopathology in distinguishing between benign and malignant breast lumps. A retrospective analysis was conducted on a cohort of patients who underwent both FNAC and subsequent histopathological examination for breast lumps at a tertiary care hospital. The diagnostic accuracy of FNAC and histopathology was assessed by comparing their results with the final diagnosis obtained through clinical follow‐up, radiological findings and other relevant investigations. The study included a total of 250 patients with breast lumps, out of which 150 were diagnosed as benign and 100 as malignant based on the final diagnosis. FNAC demonstrated an overall sensitivity of 85% and specificity of 92% in detecting malignant breast lumps. The corresponding values for histopathology were 91 and 88%, respectively. The overall accuracy of FNAC and histopathology in diagnosing breast lumps was 88 and 90%, respectively. Both FNAC and histopathology demonstrate good diagnostic accuracy in evaluating breast lumps. FNAC offers higher sensitivity for detecting malignancy, while histopathology provides better specificity for identifying benign lesions. A combined approach utilizing both techniques can enhance the diagnostic accuracy and aid in the appropriate management of patients with breast lumps. Further prospective studies with larger sample sizes are warranted to validate these findings and optimize the diagnostic algorithms for breast lump evaluation.
How to cite this article:
Chappidi Sitalata, Divya Poosarla, Sabbavarapu Mary Lavanya and Vaddadhi Sindhuri. Comparison of Diagnostic Accuracy of FNAC with Histopathology in Benign and Malignant Breast
Lumps.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.243.246
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.243.246