The study of cyto‐histopathological correlation in thyroid lesions is of significant importance in the field of diagnostic pathology. Thyroid lesions encompass a broad spectrum of abnormalities, ranging from benign nodules to malignant neoplasms. The accurate diagnosis of these lesions is crucial for appropriate patient management and treatment decisions. This study aims to investigate the correlation between cytological and histopathological findings in thyroid lesions, thereby evaluating the diagnostic accuracy and reliability of fine‐needle aspiration cytology (FNAC) as a preoperative diagnostic tool. A retrospective analysis was conducted on a cohort of patients who underwent FNAC followed by thyroidectomy or thyroid biopsy. The cytological and histopathological slides were reviewed independently by experienced pathologists. The cytological diagnoses were categorized into different diagnostic groups based on the Bethesda System for Reporting Thyroid Cytopathology. The histopathological diagnoses were classified according to the World Health Organization classification system for thyroid tumors. The study revealed a high concordance rate between cytological and histopathological diagnoses, indicating a strong correlation between the two modalities. The overall diagnostic accuracy of FNAC in detecting thyroid lesions was found to be substantial. However, the study also identified certain cases where discordance between cytological and histopathological findings occurred, highlighting the limitations and challenges associated with FNAC as a diagnostic technique. This study provides valuable insights into the cyto‐histopathological correlation in thyroid lesions. The findings support the use of FNAC as a reliable diagnostic tool for the initial evaluation of thyroid nodules. However, cautious interpretation and recognition of the limitations are essential, as discordance between cytological and histopathological diagnoses can occur. Further research and improvement in cytological techniques are warranted to enhance the accuracy and utility of FNAC in the diagnosis of thyroid lesion.
Chappidi Sitalata and Sivajyothsna Suratha. Study of Cyto‐Histopathological Correlation in Thyroid Lesions.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.230.233
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.230.233