Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Urogenital surgery and adenotonsillectomy are frequently conducted surgical procedures in the advanced pediatric age group. This study aims to investigate the impact of a single administration of gabapentin at a dosage of 15 mg kg-1 on acute pain experienced during the immediate postoperative period in patients between the ages of 8 and 14 years who undergo surgeries under general anesthesia. A total of 78 patients within the ASA categories I and II, aged 8‐14 years, who were scheduled for urogenital surgeries such as orchidopexy or urethroplasty under general anesthesia, were selected as participants for this study. These patients were randomly assigned to one of two treatment groups. Group A received an oral administration of gabapentin at a dose of 15 mg kg-1, dissolved in 5 mL of honey, two hours prior to the surgical procedure. Conversely, group B received an oral administration of 5 mL of honey alone, also two hours before the surgery. Those in gabapentin group exhibited significantly reduced perioperative fentanyl consumption compared to the control group. Additionally, patients in the gabapentin group experienced a longer duration until the first administration of rescue analgesia compared to those in Group B. It is worth noting that the treatment group exhibited an increase in sedation scores. The findings of our clinical study indicate that administering a single preemptive oral dose of gabapentin at 15 mg kg-1 may potentially decreases the need for analgesics during the perioperative period in pediatric patients. However, it is important to note that this intervention could also lead to undesirable effects, including an increase in sedation.
How to cite this article:
Kinjalben Jethalal Prajapati, Ratna Dhanesh Bhojak, Kinjal Oza and Archana Patel. Evaluation of Oral Administration of Gabapentin for Preoperative Pediatric Analgesia.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.226.229
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.226.229