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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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A Study of the Factors Precipitating Hepatic Encephalopathy in Patients of Chronic Liver Disease Visiting A Tertiary Care Hospital

Deepa Nikhil Thadani, Bhaveshkumar Maganbhai Chaudhari, Pranay R. Vaghela and Mahesh Solu
Page: 152-157 | Received 01 Jun 2023, Accepted 20 Jun 2023, Published online: 27 Jun 2023

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https://doi.org/10.36478/10.59218/makrjms.2023.152.157

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Abstract

Hepatic encephalopathy, a severe neuropsychiatric syndrome, is a frequent complication of chronic liver disease. Understanding the precipitating factors and outcomes can guide therapeutic strategies. This study aimed to identify the precipitating factors, underlying chronic liver diseases, severity and outcomes of hepatic encephalopathy. A cross-sectional hospital-based study was conducted at the Department of Medicine of Dr. Kiran C Patel Medical College and Research Institute, Bharuch, Gujarat, over a period of one year. The study comprised 100 patients with chronic liver disease who presented with or developed hepatic encephalopathy during their hospital stay. Alcoholic liver disease was the most common underlying chronic liver disease (54%). The most prevalent precipitating factor was gastrointestinal bleeding (18%). Sleep disturbance was reported by 52% of patients. According to the West haven grading system, 33% of patients presented with grade 3 hepatic encephalopathy and 23% were in grade 4. The mortality rate was 16%. Hepatic encephalopathy remains a severe complication of chronic liver disease with high mortality. Our findings emphasize the importance of early detection and intervention, particularly in managing precipitating factors, to improve outcomes.

How to cite this article:

Deepa Nikhil Thadani, Bhaveshkumar Maganbhai Chaudhari, Pranay R. Vaghela and Mahesh Solu. A Study of the Factors Precipitating Hepatic Encephalopathy in Patients of Chronic Liver Disease Visiting A Tertiary Care Hospital.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.152.157
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.152.157