Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Obstetric cholestasis is an important detectable liver disorder of pregnancy that is the cause of neonatal morbidity. The lack of any monitoring techniques to detect the progression of fetal adversity poses a further risk and leads to importance of detecting and treatment of obstetric cholestasis. Through this study I have tried to detect the maternal outcome as well as the perinatal outcome. To study the biochemical parameters pertaining to the disease and to study the mode of delivery ascertained for the delivery of the patients. In this prospective study 100 patients presenting with pruritis were studied in the tertiary railway hospital B.R. Singh from duration of June 2018 to December 2019. After ruling out other causes of pruritis and altered liver functions the patients of obstetric cholestasis were studied with their progressive liver function tests and perinatal outcome were tabulated and compared with other studies to compare the management in our institution. In our study we found that out of 26 (26.0%) patients who had Elective LUCS, 28 (28.0%) patients had Emergency LUCS and 46 (46.0%) patients had NVD. The maximum indication of was fetal distress and obstetric complication mostly associated with obstetric cholestasis was PIH, in our study 19(19.0%) patients had PIH. 54 (54.0%) patients had MSL. 2 (2.0%) patients had IUFD. Babies of 48 (48.0%) patients had Admission in NICU and babies of 30 (30.0%) patients had Apgar score <7. Obstetric cholestasis is being increasingly associated with maternal complications as PIH and the neonatal mortality and NICU admissions. Our study showed a significant amount of perinatal mortality due to obstetric cholestasis and so adequate antenatal management and timely intervention is to be taken to prevent significant perinatal mortality.
How to cite this article:
Rupa Brahma and C. S. Lee. A Prospective Study on Perinatal Outcome of Obstetric Cholestasis in a Tertiary Care Centre.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.11.84.88
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.11.84.88