Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Comparision of the Efficacy of 0.5% Levobupivacaine with a Combination of 0.5% Levobupivacaine and Hyaluronidase, in Ultrasound Guided Peripheral Nerve Block for Forearm and Hand Surgeries
Mandavilli Vijay Kanth and Sirisha Mutchi
Page: 43-47 | Received 25 Sep 2023, Published online: 11 Oct 2023
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Abstract
The advantages of the regional anesthesia are improved by the addition of adjuncts and the complications associated with the peripheral blocks using blind approaches were also decreased with the introduction of ultrasound in the medical field. Our study is to evaluate the efficacy of 0.5% Levobupivacaine with combination of 0.5% Levobupivacaine and hyaluronidase in USG guided axillary brachial plexus block for forearm and hand surgeries. Hyaluronidase drug acts as a spreading factor. The parameters evaluated were onset of sensory block, onset of motor block, duration of sensory block and time to rescue analgesia. A total of 70 patients belonging to ASA PS class 1 and 2 in the age group of 20‐60 years who underwent elective hand and forearm surgeries in the orthopedic department of medical college from to were included in the study. They were divided into 2 groups. Group A were treated with 20ml of 0.5% levobupivacaine and Group B with 20 mL of 0.5% levobupivacaine and hyaluronidase 300 units and they were given Ultrasound guided axillary brachial plexus block. The mean onset of sensory block in the Group A patients who only received 0.5% Levobupivacaine was 13.4±0.8 min and the mean onset of sensory block in Group B patients who received 300 units of hyaluronidase to 20 mL of 0.5% levobupivacaine was 10.6±0.9 min. The mean onset of motor block in the Group A patients was 14±1.45 min and the mean onset in motor block in the Group B patients was 11.8±1.6 min. The mean duration of sensory block in Group A patients who did not receive the adjunct hyaluronidase was 10.10±2.0 hrs and the mean duration of sensory block in Group B patients who received the adjunct was 7.6±1.0 hrs. The mean duration to rescue analgesia in Group A was 12.0±2 hrs and in the Group B was 9.5±1.3 hrs. The addition of 30 units of hyaluronidase to 20 mL of 0.5% levobupivacaine in the Ultrasound guided axillary block reduces the onset of sensory block, reduces the onset of motor block, therefore shortens the total analgesic time before the surgery. This study also concludes that it reduces the duration of the sensory block and also reduces the mean time to rescue analgesia.
How to cite this article:
Mandavilli Vijay Kanth and Sirisha Mutchi. Comparision of the Efficacy of 0.5% Levobupivacaine with a Combination of 0.5% Levobupivacaine and Hyaluronidase, in Ultrasound Guided Peripheral Nerve Block for Forearm and Hand Surgeries.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.11.43.47
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.11.43.47