Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Viral hepatitis is one of the leading causes of death globally with 1.4 million deaths per year. Hepatitis B and C viruses cause 95% of those deaths by causing chronic infection that can lead to cirrhosis and hepatocellular carcinoma. Primary diagnosis of HBV and HCV infection is done by serological tests for detecting antigens and antibodies against these viruses respectively. Qualitative and quantitative molecular tests are used to confirm primary diagnosis, quantify viral load, determine genotypes and plan treatment regimen for resistance mutants. In this study, we analyze the data of samples tested for Hepatitis B and C at a State Reference Laboratory for viral load testing. A total of 48,116 HBV and 43,596 HCV samples were screened for Hepatitis by ELISA over a period of 1.5 years; of which 2157 (4.48%) HBV and 842 (1.93%) HCV samples were further subjected to quantitative PCR testing for viral load.
How to cite this article:
A. Majge, J. Shah, S. Taklikar, D. Turbadkar, P. Rewale and A. Siddiqui. Beyond Routine Testing in Hepatitis B and C: Experience of A State Reference Laboratory.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.11.28.34
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.11.28.34