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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Biofilm Production and Antibiotic Sensitivity Pattern of Methicillin Resistant Coagulase Negative Staphylococcus (MR‐ CoNS) Isolates from Various Clinical Samples from a Tertiary Care Centre

Bijoy Johnson, Ramanath Karicheri and Mamta Sharma
Page: 235-239 | Received 28 Aug 2023, Published online: 30 Nov 2023

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https://doi.org/10.36478/10.59218/makrjms.2023.11.235.239

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Abstract

CoNS are typically considered as contaminants in clinical samples but have also been linked to clinically significant illnesses such as urinary tract infections, endocarditis, bloodstream infections (including neonatal sepsis) infections due to foreign bodies. This hospital study evaluated the prevalence of various species, capacity of CoNS to form biofilm their pattern of antibiotic sensitivity. Biofilm production was detected using the Congo red agar (CRA) method the Microtiter plate (MTP) method. 56% of the tested isolates developed biofilm. The isolates discovered are Staphylococcus haemolyticus (34.83%), Staphylococcus epidermis (31.93%), Staphylococcus capitis (16.77%), Staphylococcus cohnii (10.96%), Staphylococcus hominis (5.48%). The CoNS isolates exhibited resistance to cefoxitin (100%), erythromycin (94.8%), ciprofloxacin (66.7%), sulfamethoxazole/trimethoprim (66.7%), gentamicin (66.12%), clindamycin (62.9%) according to their antimicrobial susceptibility profile. The resistance rate to mupirocin was 48.5% in S. epidermidis 38.9% in S. haemolyticus isolates. All isolates showed susceptibility to vancomycin linezolid. The study’s results are essential for creating a plan to control biofilm development as an alternative method to address the spread of multidrug‐resistant CoNS in healthcare settings.

How to cite this article:

Bijoy Johnson, Ramanath Karicheri and Mamta Sharma. Biofilm Production and Antibiotic Sensitivity Pattern of Methicillin Resistant Coagulase Negative Staphylococcus (MR‐ CoNS) Isolates from Various Clinical Samples from a Tertiary Care Centre.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.11.235.239
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.11.235.239