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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Role of Magnetic Resonance Imaging in Characterizing Focal Lesions of Prostate with Histopathological Correlation

Kamala Manogna Nibhanupudi, Elamparidhi Padmanabhan, Thara Keloth, Yamini Subbiah and Umamageswari Amirthalingam
Page: 199-205 | Received 18 Nov 2023, Published online: 30 Nov 2023

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https://doi.org/10.36478/10.59218/makrjms.2023.11.199.205

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Abstract

Common conditions affecting prostate include ‐BPH, prostate cancer and prostatitis. Prostate cancer is the second most common and fifth leading cause of cancer deaths[1]. Local extension of tumor can be detected using MR imaging and assessment of tumor aggressiveness, can be done using MR spectroscopy[2]. Combined MRI and MRS provide important role in localization and staging of prostate cancer[3]. To determine the role of magnetic resonance Imaging in characterizing focal lesions in the prostate using histopathological findings as a reference standard[1]. To determine the T1 and T2 signal characteristics of various focal lesions of prostate[2]. To characterize focal lesions using magnetic resonance spectroscopy. In a total of 30 patients, who have been referred to the Department of Radio‐diagnosis, SMVMCH for MRI in suspected focal lesions of prostate or for evaluation of focal prostatic lesions diagnosed in ultrasound, during the period of November‐June 2019‐2021. The patients were subjected to MRI for T1‐T2 and MRSI characteristics, which was correlated with intraoperative and histopathological reports. Data was entered into Microsoft excel data sheet and was analyzed using SPSS 25 version software. Out of 30 patients, 14 (46.7%) had carcinoma prostate, 8 (26.7%) had BPH and 8 (26.7%) showed inflammatory changes. Sensitivity, specificity and accuracy of T2‐weighted images and MRSI were 71.4%, 87.5 %, 80.1 % (Fisher’s Exact Test showed p<0.004) and 85.7%, 87.5 % and 86.6 % (p<0.001) respectively. MRSI demonstrated higher sensitivity, specificity and accuracy compared to T2‐weighted images. T2W MRI and MR spectroscopy have a great sensitivity for detecting and distinguishing organ restricted prostate cancer from other benign causes. MR spectroscopy is more sensitive and specific than MRI alone, hence recommended for combined imaging with MRI and MR spectroscopy.

How to cite this article:

Kamala Manogna Nibhanupudi, Elamparidhi Padmanabhan, Thara Keloth, Yamini Subbiah and Umamageswari Amirthalingam. Role of Magnetic Resonance Imaging in Characterizing Focal Lesions of Prostate with Histopathological Correlation.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.11.199.205
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.11.199.205