Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by hyperglycemia and insulin resistance. While the impact of T2DM on glucose metabolism is well‐documented, its effects on serum electrolyte levels are less understood. This study aimed to investigate the association between T2DM and alterations in serum electrolyte concentrations. A cross‐sectional study was conducted on a cohort of 120 adult participants, including 50 individuals with T2DM and 50 age‐matched controls without diabetes. Serum samples were collected from all participants and levels of key electrolytes, including sodium (Na+), potassium (K+), calcium (Ca2+) and magnesium (Mg2+), were measured using standardized laboratory techniques. Clinical and demographic data were also collected and analyzed. Our findings revealed that individuals with T2DM exhibited statistically significant differences in serum electrolyte levels compared to the control group. Specifically, T2DM patients had higher serum sodium (Na+) levels (Mean±standard deviation: 82.64±5.15 mEq L-1 vs. 138.37±5.08 mEq L-1, p<0.001), lower serum potassium (K+) levels (3.82±0.42 vs. 4.42±0.65 mEq L-1, p<0.001) and serum chloride levels (ClG) (129.82±6.34 mEq L-1 vs. 180.68±6.56 mEq L-1, p<0.001). This study provides evidence of altered serum electrolyte levels in individuals with T2DM, specifically elevated serum sodium (Na+) levels and decreased serum potassium (K+) levels. These electrolyte imbalances may have clinical implications for T2DM management and highlight the need for further research to elucidate the underlying mechanisms and potential therapeutic interventions to maintain electrolyte balance in T2DM patients.
How to cite this article:
Mohd Azam Hyder and Prashanthi Rayaprolu. Study of Serum Electrolytes in Type 2 Diabetes Mellitus.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.11.132.136
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.11.132.136