Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Comparison of SpO2/FiO2 (Sf) Ratio and PaO2/FiO2 (Pf) Ratio in Mechanically Ventilated Patients with ARDS in Covid ICU for Prognosis of ARDS: A Prospective, Observational Study
Venu Gandhi, Lopa Trivedi, Kiran Mulani and Shruti Patel
Page: 12-16 | Received 22 Aug 2023, Published online: 10 Oct 2023
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Abstract
COVID‐19 frequently manifests as silent hypoxia, in which the patient has no aberrant respiratory pattern despite severe hypoxia. Arterial blood gas analysis is complicated and time‐consuming procedure for prognosis of acute respiratory distress syndrome. So, this study is aimed to derive the P/F values from S/F values which will be useful for determining the prognosis of ARDS patients on mechanical ventilation without any delay and complication. A hundred patients admitted in COVID ICU with ARDS requiring mechanical ventilation (invasive or non‐invasive) were enrolled and followed up for 10 days. Continuous vital monitoring was done and alternate day ABG analysis was done during the course of disease. At same FiO2, PaO2 and SpO2 of patients were noted and plotted on graph with SF ratio on X‐axis and PF ratio on Y‐axis. Receiver Operating Characteristic curve was plotted and linear regression equation was derived which can determine PF ratio from SF ratio. Patient’s characteristics in terms of age and gender had no significant relationship with either SF ratio or PF ratio (p>0.05). A linear regression equation was derived which states the correlation of S/F ratio and P/F ratio and was found to be statistically significant (p<0.001) PF = 1.1597SF‐35.211 (R2 = 0.8994). The results show linear correlation of PF ratio with SF ratio and so PF ratio can be derived using the above equation. It avoids repeated arterial puncture to evaluate the prognosis of patient.
How to cite this article:
Venu Gandhi, Lopa Trivedi, Kiran Mulani and Shruti Patel. Comparison of SpO2/FiO2 (Sf) Ratio and PaO2/FiO2 (Pf) Ratio in Mechanically Ventilated Patients with ARDS in Covid ICU for Prognosis of ARDS: A Prospective, Observational Study.
DOI: https://doi.org/10.36478/10.59218/makrjms.2023.11.12.16
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2023.11.12.16