Psoriasis has been shown to be an independent risk factor for myocardial infarction, particularly in young patients and severe psoriasis has been shown to be associated with increased mortality in patients with cardiovascular disease. This comprehensive concept of metabolic syndrome is of clinical significance because it can be a strong predictor of cardiovascular diseases, diabetes and stroke. A detailed history taking included duration of the disease, joint pains, smoking, alcohol consumption, diet, presence of other systemic illness, past intake of systemic agents for psoriasis and concomitant intake of medicines for other illnesses. Clinical examination included measurement of height, weight, waist circumference, hip circumference and blood pressure. The body mass index (BMI) was by weight in kg/square of height in meters. According to Indian guidelines, a BMI from 23‐24.9 is overweight, a BMI greater than or equal to 25 is moderate obesity and a BMI greater than or equal to 30 is severe obesity. We noted that presence of impaired fasting glucose is a strong predictor for developing metabolic syndrome in the patients without metabolic syndrome (OR‐6, p = 0.017). When comparing both the groups with and without metabolic syndrome, we observed significant correlation between HDL levels, TG and LDL levels and metabolic syndrome. Cholesterol levels have no significant correlation with metabolic syndrome. There was no correlation between the severity of psoriasis and occurrence of metabolic syndrome. This study has to be continued for years to know the real prevalence. all patients must be screened for cardiovascular risk factors as per the proposed guidelines at the disease onset irrespective of the disease severity and more so in those patients where systemic therapy is being considered.
Khushboo Gupta. A Study on Assessment of Comparison of Psoriatic
Patients with and Without Metabolic Syndrome.
DOI: https://doi.org/10.36478/10.59218/makrjms.2020.6.218.222
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2020.6.218.222