Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Research has indicated that when preventive antibiotics are given during a caesarean section, they dramatically decrease the occurrence of maternal postpartum fever, wound infection, endometritis, urinary tract infections, major infectious morbidity, death and length of hospital stay, when compared to a placebo. Patients who had acute cholecystitis, choledocholithiasis, and other medical conditions such as diabetes mellitus, hypertension, cardiac or renal failure, ischemic heart disease, immunosuppression and those who underwent open surgery were not included in this study. Following admission, a comprehensive medical history, physical examination findings, routine blood test results, and ultrasound report were recorded in the proforma sheet. The patients were randomly divided into two equal groups one group was assigned as the single dose group (SD), while the other group was assigned as the multiple dose group (MD). single dose (SD) group, consisting of 45 patients and multiple doses (MD) group, also consisting of 45 patients. Both groups got the intended treatment and were evaluated. Among the 90 patients, 68 (75.5%) were girls and 22 (24.4%) were males. The average age of individuals with symptomatic cholelithiasis was 44.621±13.15 years, with a minimum age of 18 years and a maximum age of 77 years. Our research suggests that using a single dosage of antibiotics before anaesthesia induction for laparoscopic cholecystectomy is equally effective as using numerous doses of antibiotics in preventing surgical site infections during the post‐operative period.
How to cite this article:
Mukesh Kumar Garg. Effectiveness of Single Dose versus Multiple Dose of Pre‐Operative Antibiotic: A Prospective Observational Study.
DOI: https://doi.org/10.36478/10.59218/makrjms.2016.716.720
URL: https://www.makhillpublications.co/view-article/1815-9346/10.59218/makrjms.2016.716.720