Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Cell block technique when compared with conventional smear provides increased cellularity, preservation of architectural pattern with excellent morphology and clear background. Hence, we have conducted the study to compare cell block technique as compared with conventional cytological smear. An institution‐based observation study was carried out on 100 serous fluids over one and half year. Serous fluid was divided into 2 parts. First part was used for conventional smear and second part was used for preparation of cell block using plasma thromboplastin method. Special stain and im uno his to chemistry were done whenever required. Maximum number of patients belong to the age group of 41‐50 years. Cellularity was more by cell block method as compared to conventional smear. 18 serous effusions diagnosed as malignant in cell block technique. Most common cause of malignant effusion was due to ovarian malignancy in 14 cases. Out of 100 cases discrepancy between conventional smear and cell block was observed in 14 cases. 3 cases which were reported as benign in conventional smear were diagnosed as malignant by cell block method. Out of 11 cases which were reported as suspicious as malignancy in conventional smear, 6 cases were diagnosed as malignant and 5 cases were diagnosed as benign by cell block method. Hence to reach conclusive diagnosis for cytological evaluation of effusion, cell block analysis is mandatory step in addition to conventional smear especially when conventional smear is suspicious for malignancy. Cell block technique can also help in identification of primary by immune his to chemistry.
How to cite this article:
S.S. Khedkar, D.P. Dangmali, V.L. Rahangdale and L.A. Nakate. Cytological Study of Serous Effusions with Conventional Smear Cytology and Cell Block Technique.
DOI: https://doi.org/10.36478/10.36478/makrjms.2025.2.53.56
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2025.2.53.56