Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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A Comparative Study of Two Methods of Phenylephrine Administration to Manage Hypotension in Caesarian Section During Spinal Anaesthesia
P. Mounika, R. Shravvya, M.D. Inamullah Khalid and Yagna Munesh Gali
Page: 257-261 | Received 24 Aug 2024, Published online: 26 Jan 2025
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Abstract
In this prospective study, injection phenylephrine was used as a vasopressor agent to prevent or treat spinal anaesthesia‐induced hypotension undergoing an elective cesarean section. Phenylephrine, when used as an infusion at a dose of 100mcg/min for preventing hypotension, was effective when compared to a bolus dose of the same drug. Even though phenylephrine infusion was effective as a vasopressor, there was a fall in heart rate occasionally as a reflex action, but it was not statistically significant. There was no incidence of bradycardia or change in rhythm. In elective cesarean sections was effective in maintaining the blood pressure and reverting the hypotension episodes. But when compared phenylephrine infusion group provided more stable blood pressures. In Group I, only 6.7% incidence of hypotension episodes, whereas in Group II, 96.7% incidence of hypotension episodes were seen, indicating phenylephrine infusion was more effective in preventing hypotension episodes. In both, the groups had similar pre‐induction systolic blood pressure, but the mean systolic blood pressure was higher in the infusion group and was statistically significant. In both groups had similar pre‐induction diastolic blood pressure., however, after the subarachanoid block, the mean DBP was higher in the infusion group and was statistically significant. Mean arterial pressure pre‐induction was similar in both the groups, but mean arterial pressure was higher in the infusion group and was statistically significant. Phenylephrine does much higher in Group I (infusion group) when compared to Group II (bolus group), which was statistically significant (P<0.001). No significant side effects were observed in the study (nausea, vomiting). There was no significant difference between the two groups in APGAR scores.
How to cite this article:
P. Mounika, R. Shravvya, M.D. Inamullah Khalid and Yagna Munesh Gali. A Comparative Study of Two Methods of Phenylephrine Administration to Manage Hypotension in Caesarian Section During Spinal Anaesthesia.
DOI: https://doi.org/10.36478/10.36478/makrjms.2025.2.257.261
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2025.2.257.261