Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
Asthma is a significant chronic condition in children, impacting their quality of life. Inhaled corticosteroids (ICS) and leukotriene receptor antagonists (LTRA) are commonly prescribed for managing pediatric asthma. However, comparative data on their efficacy and outcomes in real‐world clinical settings are sparse. This study aims to compare the efficacy, symptom control, exacerbation frequency and adherence between ICS and LTRA in pediatric asthma management. We conducted a retrospective comparative study of 100 pediatric asthma patients divided equally between those treated with ICS and those treated with LTRA. Data were collected from medical records regarding asthma control, exacerbation rates and treatment adherence over a period of one year. The ICS group demonstrated higher overall efficacy (68% vs. 56%, p=0.042) and better control of asthma symptoms with 80% achieving good symptom control compared to 60% in the LTRA group (p=0.025). Exacerbation rates were significantly lower in the ICS group, with 88% experiencing fewer than one exacerbation per year compared to 70% in the LTRA group (p=0.013). Additionally, adherence was notably higher in the ICS group (92% high adherence) compared to the LTRA group (80% high adherence, p=0.070). Inhaled corticosteroids are more effective than leukotriene receptor antagonists in managing pediatric asthma, with better symptom control, fewer exacerbations and higher treatment adherence. These findings support the continued use of ICS as the primary treatment for pediatric asthma in clinical settings.
How to cite this article:
Purushottam Rathi and Yogesh Madhukar Salunkhe. Comparative Study on the Efficacy of Inhaled Corticosteroids Versus Leukotriene Receptor Antagonists in Pediatric Asthma Management.
DOI: https://doi.org/10.36478/10.36478/makrjms.2025.2.190.194
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2025.2.190.194