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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Clinical Case Control Study of Injection Calcium Gluconate in Krait Snake Bite at Tertiary Care Centre in Tamilnadu

Jayaprasad Rajarajan, Senthil Kumaran Arjunan, Banugopanar Balaraman and Ayyappan Muthuvel
Page: 180-183 | Received 20 Oct 2024, Published online: 22 Jan 2025

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https://doi.org/10.36478/10.36478/makrjms.2025.2.180.183

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Abstract

In this study, to evaluate the effectiveness of calcium gluconate in early and complete recovery of krait snake bite admitted in government thiruvannamalai Medical College and Hospital. A prospective randomized clinical control study conducted in the Department of general medicine, Government thiruvannamalai Medical College and Hospital, thiruvannamalai. The study population are the Patients admitted with krait bite in Government thiruvannamalai Medical College and Hospital, thiruvannamalai and the study duration is 18 months and sample size of 100 patients. Results will be collected, tabulated and followed by statistically analyzation using Microsoft Excel and SPSS to detect the usefulness of calcium gluconate in krait bite. The response after calcium gluconate in the case and control group were compared. The higher number of complete recoveries was observed in <1 day of patients in case group. The p‐value is 0.001 <0.05 statistically significant were observed. Krait bites with neuroparalytic symptoms may be effectively treated with intravenous calcium gluconate therapy in combination with anti‐snake venom (ASV). Krait venom often induces presynaptic inhibition, where calcium functions as a neurotransmitter. We find that administering calcium gluconate infusion at an early stage in patients with Krait bite and neurotoxic envenomation results with reduced mortality and morbidity.

How to cite this article:

Jayaprasad Rajarajan, Senthil Kumaran Arjunan, Banugopanar Balaraman and Ayyappan Muthuvel. Clinical Case Control Study of Injection Calcium Gluconate in Krait Snake Bite at Tertiary Care Centre in Tamilnadu.
DOI: https://doi.org/10.36478/10.36478/makrjms.2025.2.180.183
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2025.2.180.183