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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Serum Magnesium Level in Type 2 Diabetes Mellitus Patients with and Without Microvascular Complication and Its Association with Glycemic Control

A. Mohammed Hussain, K. Jayasingh and I. Balaji
Page: 98-103 | Received 25 Sep 2024, Published online: 13 Dec 2024

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Abstract

This study aims to investigate the serum magnesium levels in Type 2 Diabetes Mellitus (T2DM) patients with and without microvascular complications and to explore the association between serum magnesium levels and glycemic control. An observational cross‐sectional study was conducted from June 2022‐2024 at Aarupadi Veedu Medical College, Puducherry. A total of 120 T2DM patients were included, categorized into good (HbA1c <7%) and poor glycemic control (HbA1c >7%) groups. Clinical parameters, including serum magnesium, fasting and postprandial blood sugar, HbA1c and microvascular complications, were assessed. Statistical analysis was performed using parametric tests. The study found that patients with poor glycemic control had significantly lower serum magnesium levels (1.70±0.24 mg/dL) compared to those with good control (2.09±0.19 mg/dL, p=0.001). Additionally, lower magnesium levels were strongly associated with the presence of microvascular complications such as retinopathy, nephropathy, and neuropathy. The correlation between serum magnesium and microvascular complications was significant (r=0.840, p=0.0001). Lower serum magnesium levels are associated with poor glycemic control and increased risk of microvascular complications in T2DM patients. Regular monitoring and potential magnesium supplementation could improve outcomes, emphasizing the need for comprehensive management strategies that include micronutrient assessment.


How to cite this article:

A. Mohammed Hussain, K. Jayasingh and I. Balaji. Serum Magnesium Level in Type 2 Diabetes Mellitus Patients with and Without Microvascular Complication and Its Association with Glycemic Control.
DOI: https://doi.org/10.36478/10.36478/makrjms.2025.1.98.103
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2025.1.98.103