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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Drug Utilization Pattern of Anti Microbial in the Orthopaedics Department: A Hospital Based Prospective Study

Mohamed Sajeed, Nasrin Nisha, Madhura Shirishkumar Bhosale and M.H.R.K. Gupatha Bayya
Page: 589-593 | Received 20 Nov 2024, Published online: 03 Jan 2025

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https://doi.org/10.36478/10.36478/makrjms.2025.1.589.593

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Abstract

Anti microbial are second most prescribed drugs. Inappropriate and over usage of anti microbial will lead to increase morbidity and mortality due to antimicrobial resistance. It will also increase the economic burden to patients. In Orthopaedic department, anti microbial have been used pre‐operatively and post operatively to prevent infections due to trauma and surgery. Doctors should prescribe the anti microbial rationally to prevent the risk of adverse drug reaction and anti‐microbial resistance. The present study aimed to evaluate the prescribing pattern of anti microbial in the orthopaedics out‐patient department and in‐patient wards of a tertiary care hospital. The study was conducted in the department of Orthopaedic, Dhanalakshmi Srinivasan Medical College and Hospital, Siruvachur, Tamil Nadu. Patients attending IP/OP in the department were included. We collected one month prescription data for analysis. Out all the prescriptions have antimicrobial drugs were recorded and analyzed. Microsoft excel and Statistical Package for Social Sciences (SPSS 20.0) version was used for analysis. A total of 280 prescriptions were randomly analyzed from the Orthopaedic department. Out of these, 143 prescriptions were from Orthopaedic OPD and 137 prescriptions were from Orthopaedic in‐patient ward. Parenteral route was the preferred route of administration in IPD and oral route was the preferred route of administration in OPD. The most common indication for antimicrobial prescribing was fracture of bones 186 (66.43%) patients followed by soft tissue infections in 58 (20.71%) patients. Among OPD patients, oral Cefixime (34.97 %) has been commonly prescribed. Among IPW patients fixed drug combination of intravenous Cefoperazome with Sulbactam (25.55 %) has been commonly prescribed. All these drugs were prescribed in brand names. In majority of cases, dual antimicrobial therapy was used in 35 (24.42%) OPD and 132 (96.35 %) IPW patients. Early assessment of irrational use of drugs can be well detected by frequent conduct of prescription auditing. This should be followed by analytical studies to link the drug utilization data to promote rationale use of medicines. There is a need to develop strategies to implement the antimicrobial stewardship (AMS) programme in every tertiary care hospital to prevent antimicrobial resistance in health care sector. This will improve the quality of life of patient and to reduce the economic burden.

How to cite this article:

Mohamed Sajeed, Nasrin Nisha, Madhura Shirishkumar Bhosale and M.H.R.K. Gupatha Bayya. Drug Utilization Pattern of Anti Microbial in the Orthopaedics Department: A Hospital Based Prospective Study.
DOI: https://doi.org/10.36478/10.36478/makrjms.2025.1.589.593
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2025.1.589.593